Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
應(yīng)用:
6-Hydroxy-20,21-epoxy Eplerenone 20-O-Ethyl Enol Ether is an intermediate in synthesizing 6β,21-Dihydroxy-Eplerenone (E588750). Eplerenone (E588775) is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
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